Elliptical and Parabolic Bursting, The Low-Threshold Calcium Current and PIR Bursting, Delta Oscillations

Public resources and restricted materials are identified below. Access information.

Core Readings

• The Low-Threshold Calcium Spike. Chapter 19 of Cellular Biophysics and Modeling: A primer on the systems biology of excitable cells. [DOI]
• Highlighted portions of Wang et al. 1991 on the T-type calcium current and the low-threshold spike in thalamic neurons.
• Sections titled “Types of Ionic currents” and “Summary of Intrinsic Membrane Properties” (pp. 46-57) of David McCormick’s chapter entitled Membrane properties and neurotransmitter actions.
• Yellow portions of H-current: Properties of a neuronal and network pacemaker by Luthi and McCormick.

Reading details

Luthi and McCormick. H-current: Properties of a neuronal and network pacemaker.

Slides & Notes

• Lecture slides — restricted PDF

• Supplementary slides: Low-Threshold Spikes — restricted PDF

• Supplementary slides: Elliptic and Parabolic Bursting — restricted PDF

Recordings & Tutorials

Tutorial: Elliptic and parabolic bursting tutorial

Tutorial: Low-threshold calcium spikes tutorial

Tutorial: Low-threshold calcium spikes full lecture

Tutorial: Low-threshold calcium spikes board demo

Practice

• Supplementary exercises — restricted PDF

Further Reading & Resources

• HandoutLowThresholdSpikePhasePlane — restricted PDF

Review of membrane currents

Restricted reading copies in the PDF companion — private repository access required.

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